The University of Iowa College of Public Health building is seen on Monday, Feb. 2, 2026, in Iowa City, Iowa. (Liz Sleper/The Daily Iowan)

According to the Iowa Cancer Registry’s latest report published on March 13, 2026, an estimated 21,700 new cancer cases will be diagnosed among Iowans in the coming year. The report projects that 6,400 Iowans will succumb to cancer, marking an increase of 100 deaths compared to 2025. This alarming trend underscores ongoing challenges in cancer prevention and treatment within the state.

Local Impact and Research Collaboration

In Johnson County alone, the report indicates that 165 residents are expected to die from cancer, with 6,795 survivors living with the disease. These figures highlight the significant impact of cancer on local communities and the urgent need for targeted health interventions.

This year, the Iowa Cancer Registry has partnered with the Agricultural Health Study, a long-term research initiative examining how agricultural lifestyle factors influence the health of farmers in Iowa and North Carolina. This collaboration arose from public concerns regarding pesticide use and its potential health effects.

Mary Charlton, a professor of epidemiology at the College of Public Health and a co-author of the report, emphasized the importance of this partnership. “We aim to address public concerns about environmental risk factors associated with cancer,” she said. The Agricultural Health Study has followed 31,433 male farmers and 22,145 female participants, who are either spouses of the farmers or farmers themselves, since its inception in the mid-1990s.

Cancer Rates and Environmental Factors

Interestingly, the study revealed that farmers in the cohort exhibited 13 percent fewer cancer cases than expected based on the general population rate in Iowa. Spouses reported a 10 percent reduction in cancer cases. Charlton suggested that this could be attributed to the “healthy worker effect,” whereby individuals in physically demanding occupations tend to maintain better overall health.

Despite these findings, Iowa still has the second-highest cancer rate in the United States. Charlton pointed out that while pesticides may contribute to cancer risk, the relationship is complex, given the multitude of chemicals involved. “Cancer is not one disease; it encompasses hundreds, if not thousands of diseases,” she stated.

The report also highlighted concerns over nitrate runoff into water supplies, which could be a significant contributor to cancer rates in Iowa. Charlton noted the lack of comprehensive data on water sources and their cancer risks, saying, “There’s not really a good database that tracks all your exposures over your lifetime.” This gap in data complicates efforts to understand and mitigate cancer risk.

Furthermore, Iowa’s pesticide reporting system is less sophisticated than those in states like California. Charlton explained that more detailed reporting could help identify which pesticides are applied in specific areas and their potential health impacts on residents nearby.

As the 2026 cancer report underscores the urgency of addressing cancer rates in Iowa, Charlton expressed hope that it will prompt further research and data collection. “We know that Iowans are concerned about environmental risk factors, and we hope this report provides some helpful context while reinforcing the need for more research,” she said.

The findings from the Iowa Cancer Registry serve as a crucial reminder of the ongoing battle against cancer and the need for continued vigilance in public health initiatives.